Conductor and composer, particularly associated with the operas of Wagner and the Italian repertory, Marinuzzi was born and studied in Palermo. He began his career in Palermo as well, conducting the local premieres of Tristan und Isolde (1909), and Parsifal (1914). He then appeared in Rome and Milan, where he conducted several local premieres (mostly Wagner operas) and many revivals of rarely performed operas such as Lucrezia Borgia, La straniera, Beatrice di Tenda and L’incoronazione di Poppea. In 1930 he conducted the world premiere of Ildebrando Pizzetti’s Lo straniero.
Marinuzzi made guest appearances at the Paris Opéra, the Royal Opera House in London, and the Monte Carlo Opera, where he conducted the world premiere of Puccini’s La rondine in 1917. He was artistic director of the Chicago Opera Association from 1919 to 1921, and the Rome Opera from 1928 to 1934.
He left a noted recording of La forza del destino (1941), with Maria Caniglia, Galliano Masini, Carlo Tagliabue, Ebe Stignani, Tancredi Pasero, and Saturno Meletti. Marinuzzi died in Milan in 1945.